Methodologies in the Analysis of Phenolic Compounds in Roselle (Hibiscus sabdariffa L.): Composition, Biological Activity, and Beneficial Effects on Human Health

Roselle (Hibiscus sabdariffa L.), as an edible flower, has long provided array of positive effects on human health. This benefit is a result phenolic compounds that are naturally present mainly in the calyx. Plentiful medicinal remedies and functional foods based this flower available worldwide, supported by studies recent decades. paper aims to provide comprehensive review composition, biological activity, beneficial health roselle. was performed accordance with Preferred Reporting Items for Systematic reviews Meta-Analyses (PRISMA) guidelines. A structured search published literature phenolics compositions roselle required prior evaluation validity reported analytical methods. Reliable identification quantification can be achieved employing proper extraction separation With ample alternative methods discussed here, aid comprehending selecting most appropriate method particular study. The applications highlighted indicated acids, flavonoids, their derivatives have been identified quantified range activities It also disclosed composition concentration vary due growth factors, cultivars, environmental influence. Finally, apart from research progress carried out during last ten years, proposed relevant future works.